stem cells

Scientists discover bladder cancer stem cell

Weissman2.jpgResearchers at Stanford’s School of Medicine have identified the first human bladder cancer stem cell and revealed how it works to escape the body’s natural defenses.

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Proposed NIH stem cell guidelines dismay leading Stanford researcher

Weissman2.jpgThe director of stem cell research at the Stanford University School of Medicine says he is troubled by draft guidelines issued today by the National Institutes of Health that would prohibit federal funding for research on stem cell lines created through a technique sometimes referred to as “therapeutic cloning” or somatic cell nuclear transfer.

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New 'bioscaffold' technique may help stem cells build solid organs

scaffolding.jpgResearchers have taken a step toward the goal of enabling stem cells to become transplantable organs such as livers or pancreases by developing a "bioscaffold" technique that can provide a reliable supply of blood to a developing organ.

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Source of cancer stem cells' resistance to radiation discovered at Stanford

cancerstemcells.jpgVIDEO: A pathway that shields normal stem cells from DNA damage appears to also help cancer stem cells withstand radiation treatment for the disease.

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Researchers create first functional stem cell niche

Weissman.jpgLike it or not, your living room says a lot about you. Given a few moments to poke around, a stranger could get a good idea of your likes and dislikes, and maybe even your future plans. Medical school scientists, employing a similar "peeping Tom" tactic to learn more about how stem cells develop, have taken a significant step forward by devising a way to re­create the cells' lair—a microenvironment called a niche—in an animal.

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Scientists identify new kind of stem cell found in testes

Reijo-Pera.jpgScientists at the School of Medicine and at UCSF have succeeded in isolating stem cells from human testes. The cells bear a striking resemblance to embryonic stem cells—they can differentiate into each of the three main types of body tissue—but the researchers caution against viewing them as one and the same.

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Study sheds light on key trigger of stem cell differentiation

Nusse.jpgClusters of mouse embryonic stem cells called embryoid bodies more closely approximate true embryos in organization and structure than previously thought, according to researchers at the School of Medicine. Harnessing the signals that influence the cells' fate may help researchers more accurately direct the differentiation of embryonic stem cells for use in therapy.

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Stanford building nation’s largest stem cell center

stem_cell_grdbrk.jpgThe School of Medicine took one step closer to opening the nation’s largest stem cell research facility with groundbreaking ceremonies Oct. 27 for the Lorry I. Lokey Stem Cell Research Building. The event followed a symposium in which researchers described some of the potential of stem cells in treating diseases as diverse as leukemia and Parkinson’s disease.

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Scientists pinpoint key proteins in blood stem cell replication

julien_sage.jpgA family of cancer-fighting molecules helps blood stem cells in mice decide when and how to divide, say medical school researchers. "This is an important step in understanding the initiation of human cancer at a cellular level," said Patrick Viatour, PhD, a postdoctoral scholar who performed the research in the laboratory of Julien Sage, PhD.

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Scientists confirm existence of elusive muscle stem cell

skeletal_muscle_1.jpgA single cell can repopulate damaged skeletal muscle in mice, say medical school scientists who devised a way to track the cell's fate in living animals. Identifying and isolating such a cell in humans would have therapeutic implications for disorders such as muscular dystrophy, muscle injury and muscle wasting due to aging, disuse or disease.

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